Adipose tissue-derived stromal cells for the repair of...

C - Chemistry – Metallurgy – 12 – N

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C12N 5/00 (2006.01) C12N 5/077 (2010.01) A61K 35/44 (2006.01) A61P 27/02 (2006.01)

Patent

CA 2465908

The invention provides compositions and methods for the use of adipose tissue- derived stromal cells for the treatment and repair of any ocular-associated tissue defect, including but not limited to those secondary to trauma, metabolic disease, inborn errors, or surgery. The adipose tissue-derived stromal cells are cultured in the undifferentiated, differentiated or adipocyte state either alone or in the presence of biocompatible material. The resulting materials are employed surgically to correct a variety of correct intra-ocular defects.

La présente invention concerne des compositions et des procédés d'utilisation de cellules stromales dérivées d'un tissu adipeux dans le traitement et la réparation d'un défaut du tissu oculaire quel qu'il soit, y compris entre autres ceux apparaissant après un traumatisme, une maladie métabolique, des erreurs innées ou une chirurgie. Les cellules stromales dérivées d'un tissu adipeux sont cultivées à l'état non différencié, différencié ou d'adipocyte, soit seuls, soit en présence d'une substance biocompatible. Les substances ainsi obtenues sont employées en chirurgie pour corriger une grande variété de défauts interoculaires.

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