Adjltvant compositions comprising a mineral salt and another...

Details Adjltvant compositions comprising a mineral salt and another... Adjltvant compositions comprising a mineral salt and another...

C - Chemistry, Metallurgy

07

H

C07H 15/12 (2006.01) A61K 39/09 (2006.01) A61K 39/10 (2006.01) A61K 39/102 (2006.01) A61K 39/20 (2006.01) A61K 39/21 (2006.01) A61P 37/04 (2006.01) C07H 11/00 (2006.01) C07H 13/00 (2006.01) C07H 15/00 (2006.01) C07K 14/005 (2006.01) C07K 14/135 (2006.01) C07K 14/16 (2006.01) C07K 14/18 (2006.01) C07K 14/195 (2006.01) C07K 14/235 (2006.01) C07K 14/285 (2006.01) C07K 14/315 (2006.01) C07K 17/00 (2006.01) C07K 1/107 (2006.01)

Patent

CA 2625156

Adjuvant compositions for modulating an immune response to an antigen administered to a host comprise a mineral salt adjuvant and at least one other adjuvant. The compositions provide an adjuvanting effect on an antigen which is greater than the adjuvanting effect attainable by one of the adjuvants alone. An antigen is covalently bonded to a glycolipid analog to provide a discrete molecule which exhibits an enhanced adjuvanting effect on the antigen which is greater than the adjuvanting effect attainable in the absence of such covalent bonding.

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