Adjuvant activity of gastrointestinal peptides

A - Human Necessities – 61 – K

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A61K 39/39 (2006.01)

Patent

CA 2591044

Gastrointestinal peptides (GPs) have been found to function as vaccine adjuvants, and in particular as mucosal adjuvants. The invention provides an immunogenic composition comprising: (a) a GP adjuvant; and (b) an antigen. The composition is preferably suitable for mucosal administration e.g. intranasal administration.

Selon cette invention, des peptides gastro-intestinaux (GP) fonctionnent en tant qu'adjuvants de vaccin, et plus particulièrement en tant qu'adjuvants des muqueuses. Plus spécifiquement, l'invention concerne une composition immunogène comprenant: (a) un adjuvant de GP, et (b) un antigène. Cette composition est de préférence adaptée à une administration par les muqueuses, par ex. une administration intranasale.

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