Adjuvant chemotherapy for anaplastic gliomas

A - Human Necessities – 61 – K

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A61K 31/15 (2006.01) A61K 31/13 (2006.01) A61K 31/70 (2006.01) A61P 35/00 (2006.01) G01N 33/573 (2006.01)

Patent

CA 2617492

The present invention involves the use of nitrone free radical trapping agents in the treatment and prevention of gliomas. The agents may be used alone or combined with other traditional chemo- and radiotherapies and surgery, to treat or prevent glioma occurrence, recurrence, spread, growth, metastasis, or vascularization.

La présente invention concerne l'utilisation d'agents de piégeage de radicaux libres de type nitrone dans le traitement et la prévention de gliomes. Ces agents peuvent être utilisés de manière isolée ou en combinaison avec d'autres chimiothérapies et radiothérapies ainsi qu'une chirurgie pour traiter ou prévenir l'apparition, la récidive, la propagation, la croissance, la métastase ou la vascularisation d'un gliome.

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