Adjuvant complexes

Details Adjuvant complexes Adjuvant complexes

A - Human Necessities

61

K

A61K 39/39 (2006.01)

Patent

CA 2064911

2064911 9103256 PCTABS00003 ''Empty'' iscom matrices, i.e. formed without an antigen, have been found to provide an adjuvant formation for a separate antigen in a vaccine formulation, the antigen being associated with a bacterium or mycoplasma. It has also been found that these and conventional iscoms can be formed without removing the solubilising agent used for the antigen. In each case, the iscom can be 3-dimensional or, if formed without phospholipid, 2-dimensional. The glycoside is preferably Quil A and the sterol is preferably cholesterol.

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