Adjuvant for vaccines

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/39 (2006.01) A61K 39/116 (2006.01) A61K 39/295 (2006.01) A61P 31/00 (2006.01) A61P 37/04 (2006.01)

Patent

CA 2402935

The invention relates to a vaccine containing a first vaccine adjuvanted with an oil-in-water emulsion comprising 5 % squalene, 0.5 % polysorbate 80, and 0.5 % sorbitan trioleate in an aqueous citrate buffer, pH 6.5. The inventive vaccine also contains a non-adjuvanted second vaccine that serves as a combination partner for the simultaneous, separate or temporally gradual utilization for the immunization against viral, bacterial or parasitic infectious diseases.

L'invention concerne un vaccin comprenant un premier vaccin auquel a été additionnée une émulsion oléoaqueuse contenant 5 % de squalène, 0,5 % de Polysorbate 80 et 0,5 % de trioléate de sorbitane dans une solution aqueuse tampon de citrate de pH 6, 5. Ledit vaccin comprend un deuxième vaccin sans adjuvant, servant de partenaire de combinaison pour une utilisation simultanée, séparée, ou étalée dans le temps à des fins d'immunisation contre des maladies infectieuses d'origine virale, bactérienne ou parasitaire.

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