Adjuvant formulation comprising a submicron oil droplet...

A - Human Necessities – 61 – K

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167/129, 167/103

A61K 39/39 (2006.01) A61K 9/00 (2006.01) A61K 9/107 (2006.01)

Patent

CA 2017507

An adjuvant composition, comprising a metabolizable oil and an emulsifying agent, wherein the oil and the detergent are present in the form of an oil-in-water emulsion having oil droplets substantially all of which are less than 1 micron in diameter. In preferred embodiments, the emulsifying agent is also an immunostimulating agent, such as a lipophilic muramyl peptide. Alternatively, an immunostimulating agent separate from the emulsifying agent can be used.

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