Adjuvant-sparing multi-dose influenza vaccination regimen

A - Human Necessities – 61 – K

Patent

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A61K 39/145 (2006.01)

Patent

CA 2657989

An influenza vaccine is administered by a multi-dose regimen, in which (i) a first dose is administered with an adjuvant and (ii) a later dose is administered either without an adjuvant or with a different adjuvant. Thus the invention provides the benefits of a two-dose regimen without also doubling the supply need for a given adjuvant.

L'invention concerne un vaccin contre la grippe à administrer par un régime multidose selon lequel (i) une première dose est administrée avec un adjuvant et (ii) une dose suivante est administrée soit sans adjuvant soit avec un adjuvant différent. L'invention a donc les avantages d'un régime à deux doses sans quantité doubler la nécessaire d'un adjuvant donné.

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