Adjuvanted meningococcus compositions

C - Chemistry – Metallurgy – 07 – H

Patent

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Details

C07H 21/02 (2006.01) A61K 39/02 (2006.01) A61K 39/095 (2006.01) A61K 39/385 (2006.01)

Patent

CA 2462646

A combination of CpG oligonucleotides and polymer microparticles is an extremely effective adjuvant for Neisserial antigens. The invention therefore provides a composition comprising: (a) a Neisserial antigen; (b) a CpG oligonucleotide; and (c) a biodegradable polymer microparticle.

L'invention concerne une combinaison d'oligonucléotides CpG et de microparticules polymères qui constitue un adjuvant extrêmement efficace pour des antigènes de Neisseria. L'invention concerne donc une composition comprenant (a) un antigène de Neisseria; (b) un oligonucléotide CpG; et (c) une microparticule polymère biodégradable.

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