Adjuvants for nucleic acid vaccines

A - Human Necessities – 61 – K

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Details

A61K 39/39 (2006.01) A61P 37/04 (2006.01)

Patent

CA 2462582

The present invention relates to the use of inducible nitric oxide synthase (iNOS) inhibitors as vaccine adjuvants, and in a preferred aspect of the present invention they are used for adjuvanting nucleic acid vaccines. The present invention further provides pharmaceutical compositions comprising an antigen and the inhibitor.

La présente invention a trait à l'utilisation d'inhibiteurs de l'oxyde nitrique synthase inductible (iNOS) en tant qu'adjuvants de vaccins. Selon un aspect préféré de l'invention, ces derniers sont utilisés comme adjuvants de vaccins à base d'acides nucléiques. La présente invention concerne également des compositions pharmaceutiques contenant un antigène et lesdits inhibiteurs.

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