Adjuvants for rectal delivery of drug substances

Details Adjuvants for rectal delivery of drug substances Adjuvants for rectal delivery of drug substances

A - Human Necessities

61

K

167/160

A61K 47/00 (2006.01) A61K 9/02 (2006.01)

Patent

CA 1165688

A B S T R A C T A method and drug form for enhancing the rate of absorption of a rectally administered drug from the rectal compartment into the blood stream of a warm blooded animal. The method includes the steps of pre- paring a drug form capable of being rectally administer- ed. The drug form comprises a therapeutically effective unit dosage amount of a selected drug of the type which is capable of being absorbed into the blood stream from the rectal compartment and hydroxy aryl or hydroxy aralkyl acids or salts, amides or esters thereof, the hydroxy aryl or hydroxy aralkyl acids or salts, amides or esters thereof being present in the drug form in a sufficient amount to be effective in enhancing the drug absorption rate, when rectally administering the drug form to warm blooded animals.

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