Administration of active agents, including 5-ht receptor...

Details Administration of active agents, including 5-ht receptor... Administration of active agents, including 5-ht receptor...

A - Human Necessities

61

K

A61K 31/404 (2006.01) A61F 2/02 (2006.01) A61F 5/41 (2006.01) A61K 9/00 (2006.01) A61K 31/00 (2006.01) A61K 31/135 (2006.01) A61K 31/137 (2006.01) A61K 31/357 (2006.01) A61K 31/40 (2006.01) A61K 31/4045 (2006.01) A61K 31/4178 (2006.01) A61K 31/4468 (2006.01) A61K 31/517 (2006.01) A61K 31/519 (2006.01) A61K 31/551 (2006.01) A61K 31/5513 (2006.01) A61K 45/06 (2006.01) A61P 15/00 (2006.01)

Patent

CA 2305293

A method is provided for delaying the onset of ejaculation in an individual. The method preferably involves administration of an antidepressant drug, a serotonin agonist or antagonist, an adrenergic agonist or antagonist, an adrenergic neurone blocker, or a derivative analog thereof, within the context of an effective dosing regimen. The preferred mode of administration is transurethal; however, the selected active agent may also be delivered via intracavernosal injection or using alternative routes. Pharmaceutical formulations and kits are provided as well.

Le procédé de l'invention consiste à retarder la survenue de l'éjaculation chez un individu et notamment à administrer un médicament antidépresseur, un agoniste ou antagoniste de la sérotonine, un agoniste ou antagoniste adrénergique, un agent bloquant les neurones adrénergiques, ou un analogue dérivé de ces substances, dans le cadre d'un schéma posologique efficace. Le mode préféré d'administration est un mode transurétral (figure), cependant, l'agent actif choisi peut également être administré par injection intracaverneuse ou par d'autres voies. L'invention concerne également des formulations et coffrets pharmaceutiques.

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