Administration of agents for the treatment of inflammation

Details Administration of agents for the treatment of inflammation Administration of agents for the treatment of inflammation

A - Human Necessities

61

K

A61K 39/395 (2006.01) C07K 16/28 (2006.01)

Patent

CA 2477178

A method of chronically reducing a patient's pathological inflammation via the administration of an agent that specifically binds to an alpha-4 integrin or a dimer comprising an alpha-4 integrin is disclosed. The agent provided must have a binding affinity such that administration is sufficient to suppress pathological inflammation, and the agent is administered chronically to provide long-term suppression of pathological inflammation.

L'invention concerne une méthode de réduction chronique d'une inflammation pathologique d'un patient par le biais de l'administration d'un agent se liant spécifiquement à une intégrine .alpha.-4 ou à un dimère comprenant une intégrine .alpha.-4. Cet agent doit présenter une affinité de liaison de sorte que l'administration soit suffisante pour supprimer une inflammation pathologique, et l'agent est administré de manière chronique afin d'obtenir une suppression à long terme de l'inflammation pathologique.

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