A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/437 (2006.01) A61K 31/4985 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2683444
In accordance with the present invention, compounds are provided which are useful in a method or in the manufacture of a medicament for post-transcriptionally inhibiting the expression of VEGF in a subject in need thereof comprising inhibiting VEGF mRNA translation by orally administering said medicament once, twice or thrice daily to the subject.
La présente invention concerne des composés utilisés dans un procédé ou dans la fabrication d'un médicament visant à inhiber de manière post-transcriptionnelle l'expression du facteur de croissance de l'endothélium vasculaire (VEGF) chez un sujet nécessitant un tel traitement, ledit procédé consistant à inhiber la traduction de l'ARNm du facteur de croissance VEGF en administrant ce médicament par voie orale audit sujet à raison d'une, deux ou trois fois par jour.
Cao Liangxian
Davis Thomas
Elfring Gary L.
Hirawat Samit
Miller Langdon
Osler Hoskin & Harcourt Llp
Ptc Therapeutics Inc.
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