Administration of monoamine acridines in cholinergic...

Details Administration of monoamine acridines in cholinergic... Administration of monoamine acridines in cholinergic...

A - Human Necessities

61

K

167/227, 260/266

A61K 31/47 (2006.01) C07D 219/10 (2006.01)

Patent

CA 1335813

A method for treating central nervous system or peripheral nervous system cholinergic deficit states such as Alzheimer's disease in a mammal, said method comprising administering to said mammal an amount of a monoamine acridine derivative effective in the treatment of a cholinergic deficit state and for a time sufficient to achieve a suitable blood level to treat said cholinergic deficit state. The preferred monoamine acridine derivative is 1,2,3,4-tetrahydro-5- aminoacridine. A unit dosage pharmaceutical composition of matter comprising an effective amount of said monoamine acridine derivative sufficient to treat said cholinergic deficit state and a pharmaceutically acceptable inert carrier therefor is also disclosed.

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