Administration of nucleic acid sequence to female animal to...

A - Human Necessities – 61 – K

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A61K 48/00 (2006.01) A01K 67/027 (2006.01) A61K 31/7088 (2006.01) A61K 38/18 (2006.01) A61P 5/00 (2006.01) A61P 15/14 (2006.01) C07K 14/60 (2006.01) C12N 15/18 (2006.01) C12N 15/85 (2006.01)

Patent

CA 2430921

Growth is improved by utilizing growth enhancement potential methodology to administer a nucleic acid sequence, such as GHRH or an analog, to a female animal, preferably through a parenteral route of administration. Piglets born from sows injected with DNA encoding GHRH are larger, and effects ae demonstrated in subsequent pregnancies without additional administration(s) of the vector.

La croissance est améliorée au moyen d'une technique d'amélioration du potentiel de la croissance, laquelle technique consiste à administrer une séquence d'acides aminés, telle que GHRH ou un analogue, à un animal femelle, de préférence par administration par voie parentérale. Les porcelets nés de truies auxquelles on a injecté un ADN codant pour GHRH, sont plus gros. Ces effets sont démontrés lors de gestations ultérieures sans administration(s) supplémentaire(s) du vecteur.

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