A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/708 (2006.01) A61P 31/14 (2006.01)
Patent
CA 2537450
This invention relates to methods for treating or preventing hepatitis C virus infections in mammals using Toll-Like Receptor (TLR)7 ligands and prodrugs thereof. More particularly, this invention relates to methods of orally administering a therapeutically effective amount of one or more prodrugs of TLR7 ligands for the treatment or prevention of hepatitis C viral infection. Oral administration of these TLR7 immunomodulating ligands and prodrugs thereof to a mammal provides therapeutically effective amounts and reduced undesirable side effects.
L'invention concerne des procédés de traitement et de prévention des infections au virus de l'hépatite C chez les mammifères à l'aide de ligands récepteur de type Toll (TLR7) et de leurs prodrogues. L'invention concerne notamment des procédés d'administration orale d'une quantité thérapeutiquement efficace d'au moins un prodrogue de ligands TLR7 pour le traitement ou la prévention de l'infection au virus de l'hépatitie C. L'administration orale de ces ligands d'immunomodulation TLR7 et de leurs prodrogues à un mammifère permet d'obtenir des quantités thérapeutiquement efficaces de ces ligands et de leurs prodrogues et des effets secondaires indésirables réduits.
Anadys Pharmaceuticals Inc.
Smart & Biggar
LandOfFree
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