Adp-ribosyl transferase fusion variant proteins

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 9/10 (2006.01) A61K 9/19 (2006.01) A61K 38/45 (2006.01) A61K 47/42 (2006.01) A61K 47/48 (2006.01) A61P 9/00 (2006.01) A61P 25/00 (2006.01) A61P 35/00 (2006.01) A61P 35/04 (2006.01) C07K 14/435 (2006.01) C07K 19/00 (2006.01)

Patent

CA 2709428

The present invention relates to novel chimeric C3-like Rho antagonists and their use for promoting repair and neuron survival in injured mammalian central and peripheral nervous system and for treating or preventing cancer.

La présente invention concerne de nouveaux antagonistes chimériques Rho similaires au C3, et leur utilisation pour promouvoir la réparation et la survie neuronale dans le système nerveux périphérique et central d'un mammifère blessé et pour traiter ou prévenir le cancer.

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