Adrenergic amidines

Details Adrenergic amidines Adrenergic amidines

C - Chemistry, Metallurgy

07

D

260/251, 260/314

C07D 405/10 (2006.01) C07D 233/00 (2006.01) C07D 233/22 (2006.01) C07D 239/06 (2006.01) C07D 239/26 (2006.01)

Patent

CA 1259995

ADRENERGIC COMPOUNDS Abstract of the Disclosure Disclosed herein are adrenergic compounds represented by the formula Image wherein m is 0, 1 or 2; R1, R2, R3 are taken from the group consisting of hydrogen, hydroxy, loweralkyl, loweralkoxy, halo, or NHSO2R wherein R is taken from the group consisting of hydrogen, loweralkyl or arylalkyl, provided that R1, R2, R3 cannot simultaneously be hydrogen, and provided that when one of R1, R2, R3 is halo, the other two cannot simultaneously be hydrogen; R1 and R2 or R2 and R3 taken together can form a methylenedioxy or ethylenedioxy bridge; and R4 and R5 are hydrogen or taken together form a closed ring of the formula Image wherein n is 1 or 2, and the dashed line represents a single or double bond when n is 1, and R6 is taken from the group consisting of hydrogen, loweralkyl, or arylalkyl, and the pharmaceutically acceptable salts thereof.

483266

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