Adrenic acid receptor and uses thereof

Details Adrenic acid receptor and uses thereof Adrenic acid receptor and uses thereof

C - Chemistry, Metallurgy

07

K

C07K 14/705 (2006.01) A61K 31/202 (2006.01) A61K 45/00 (2006.01) C12N 15/85 (2006.01) C12P 21/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/566 (2006.01) G01N 33/74 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2392305

This invention relates to the identification of an orphan G-protein coupled receptor PFI- O11 (and variants thereof) as a receptor of adrenic acid, and the use of adrenic acid (and analogues or mimetics thereof) as modulators for PFI-011. It also relates to screening methods to identify agonists and antagonists for this adrenic acid receptor.

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