C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/16 (2006.01) A61K 38/35 (2006.01) A61K 39/395 (2006.01) C07K 14/695 (2006.01) C07K 14/72 (2006.01) C07K 16/00 (2006.01) C12N 5/02 (2006.01)
Patent
CA 2388198
The present invention rotates to a mammalian adrenocorticotropic hormone receptor. The invention is directed toward the isolation, characterization and phar- macological use of mammalian adrenocorticotropic hor- mone receptor, the gene corresponding to this receptor, a recombinant eukaryotic expression construct capable of expressing a mammalian-adrenocorticotropic hormone receptor in cultures of transformed eukaryotic cells and such cultures of transformed eukaryotic cells that syn- thesize mammalian adrenocorticotropic hormone recep- tor. The invention also provides methods for screening ACTH R agonists and antagonists in vitro using prepar- ations of receptor from such cultures of eukaryotic cells transformed with a recombinant eukaryotic expression construct comprising the ACTH R receptor gene. The in- vention specifically provides human and bovine ACTH R genes.
Cone Roger D.
Mountjoy Kathleen G.
Mbm Intellectual Property Law Llp
State Of Oregon Acting By And Through The Oregon State Board Of Higher Education
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