Adrenomedullin and adrenomedullin binding protein for...

Details Adrenomedullin and adrenomedullin binding protein for... Adrenomedullin and adrenomedullin binding protein for...

A - Human Necessities

61

K

A61K 38/00 (2006.01)

Patent

CA 2562957

Methods of treating a mammal at risk for ischemia-reperfusion injury are provided. The methods comprise administering an adrenomedullin binding protein- 1 (AMBP-1) to the mammal in sufficient amount to reduce the injury. Also provided are methods of treating a mammal at risk for ischemia-reperfusion injury to the bowel. The methods comprise administering adrenomedullin to the mammal in sufficient amount to reduce the injury.

La présente invention concerne des procédés permettant de traiter un mammifère présentant un risque de lésions ischémiques ou de reperfusion. Le procédé consiste en une administration d'une protéine-1 de liaison à l'adrénomodulline (AMBP-1) en quantité suffisante au mammifère pour réduire la lésion. L'invention concerne également des procédés permettant de traiter un mammifère présentant un risque de lésions ischémiques ou de reperfusion dans l'intestin. Le procédé consiste en une administration au mammifère d'une quantité d'adrénomodulline pour réduire la lésion.

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