A - Human Necessities – 61 – M
Patent
A - Human Necessities
61
M
A61M 1/36 (2006.01) A61M 1/02 (2006.01) B01J 20/26 (2006.01) B01J 20/28 (2006.01)
Patent
CA 2603073
It is intended to provide an adsorbent by which cells contained in the blood typified by activated leukocytes such as granulocytes and monocytes and cancer cells can be removed and cytokines promoting the activation of cells remaining therein can be removed and which has a high morphological stability without any fear of pressure loss. Namely, an adsorbent having a Zeta potential of -20 mV or above and being capable of adsorbing granulocytes and monocytes in the blood; an adsorbent for treating cancer being capable of adsorbing an immunosuppressive protein; an adsorbent characterized by having a double- layered structure composed of a net and a non-woven fabric; and a blood circulation column packed with any one of the adsorbents as described above.
L~invention permet d~obtenir un adsorbant par lequel des cellules contenues dans le sang, comme des leucocytes activés tels que des granulocytes et monocytes et des cellules cancéreuses, peuvent en être retirées, et des cytokines favorisant l'activation des cellules restantes peuvent en être retirées, et qui possède une haute stabilité morphologique sans risque de perte de tension. L~invention concerne plus précisément un adsorbant ayant un potentiel zêta de -20 mV ou plus, et étant capable d'adsorber des granulocytes et des monocytes dans le sang ; un adsorbant pour traiter le cancer, capable d'adsorber une protéine immunosuppressive ; un adsorbant caractérisé en ce qu~il a une structure en double couche, composée d'un filet et d~un tissu non tissé ; et une colonne de circulation sanguine remplie de l~un quelconque des adsorbants décrits ci-dessus.
Oozeki Takeshige
Sato Katsuhisa
Shimagaki Masaaki
Teramoto Kazuo
Wada Shigehisa
Fetherstonhaugh & Co.
Toray Industries Inc.
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