Adsorbent for endotoxin, tumor necrosis factor-.alpha. or...

Details Adsorbent for endotoxin, tumor necrosis factor-.alpha. or... Adsorbent for endotoxin, tumor necrosis factor-.alpha. or...

C - Chemistry, Metallurgy

07

K

C07K 1/18 (2006.01) A61M 1/36 (2006.01) A61M 1/38 (2006.01) B01D 15/00 (2006.01) B01J 20/26 (2006.01) C07K 14/52 (2006.01) C07K 14/525 (2006.01) C07K 14/54 (2006.01) C07K 14/55 (2006.01) C08B 37/00 (2006.01)

Patent

CA 2208745

An adsorbent includes styrene-divinylbenzene copolymer having sulfonic acid groups for adsorbing endotoxin, tumor necrosis factor-.alpha. (TNF-.alpha.), and/or interleukins. A method for adsorbing and removing endotoxin, TNF-.alpha., and/or interleukins, includes contacting an adsorbent with a fluid containing endotoxin, TNF-.alpha., and/or interleukin. In an adsorber for adsorbing endotoxin, TNF-.alpha., and/or interleukins, the adsorbent is charged in a vessel having an inlet and an outlet for fluid.

Un adsorbant comprend un copolymère de styrène-divinylbenzène portant des groupes acide sulfonique pour adsorber des endotoxines, le facteur de nécrose tumorale-alpha (TNF-alpha) et/ou les interleukines. Une méthode pour adsorber et éliminer les endotoxines, le TNF-alpha et/ou les interleukines, comprenant la mise en contact d'un adsorbant avec un fluide contenant l'endotoxine, le TNF-alpha et/ou l'interleukine. Dans un appareil d'adsorption destiné à adsorber une endotoxine, le TNF-alpha et/ou les interleukines, l'adsorbant est placé dans un contenant doté d'une voie d'entrée et d'une voie de sortie du fluide.

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