Adsorptive membranes for trapping viruses

B - Operations – Transporting – 01 – D

Patent

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Details

B01D 71/34 (2006.01) A61L 2/00 (2006.01) B01D 61/00 (2006.01) B01D 67/00 (2006.01) B01D 69/02 (2006.01) B01D 69/14 (2006.01) B01J 20/32 (2006.01) B01J 47/12 (2006.01)

Patent

CA 2655873

A disposable, virus-trapping membrane, and a corresponding method to remove viruses from solution are described. The membrane includes a disposable, micro-porous filter membrane and a ligand immobilized on the membrane. The ligand irreversibly and selectively binds viruses. The ligand also has a pKa sufficiently high to repel antibodies via electrostatic charge repulsion.

La présente invention concerne une membrane jetable destinée à piéger des virus, et un procédé correspondant destiné à retirer des virus d'une solution. La membrane comprend une membrane-filtre micro-poreuse jetable et un ligand immobilisé sur la membrane. Le ligand se lie aux virus de manière irréversible et sélective. Le ligand a aussi un pKa suffisamment élevé pour repousser des anticorps par répulsion des charges électrostatiques.

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