Adult t-cell leukemia antigens, method for their preparation...

A - Human Necessities – 61 – K

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167/129, 167/43,

A61K 39/385 (2006.01) C12N 11/00 (2006.01) G01N 33/532 (2006.01) G01N 33/543 (2006.01) G01N 33/569 (2006.01) G01N 33/574 (2006.01)

Patent

CA 1197776

ABSTRACT An insolubilized antigen is disclosed which comprises an insoluble support having immobilized thereon an adult T-cell leukemia associated antigen selected from the group consisting of a soluble cytoplasmic protein of an adult T-cell leukemia cell and a solubilized protein of an adult T-cell leukemia virus. Also, a process for pre- paring the insolubilized antigen and a method for assaying an antibody to adult T-cell leukemia associated antigen according to fluorescence immunoassay or enzyme immunoassay using the insolubilized antigen are disclosed. The use of the insolubilized antigen permits of speedy assay of the antibody in large amounts of test sample sera.

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