Adzymes and uses thereof

Details Adzymes and uses thereof Adzymes and uses thereof

C - Chemistry, Metallurgy

07

K

C07K 19/00 (2006.01) A61K 38/48 (2006.01) C12N 1/16 (2006.01) C12N 1/20 (2006.01) C12N 5/10 (2006.01) C12N 9/76 (2006.01) C12N 15/52 (2006.01) C12N 15/62 (2006.01)

Patent

CA 2563397

Disclosed is a family of novel protein constructs, useful as drugs and for other purposes, termed "adzymes," comprising an address moiety and a catalytic domain. A preferred adzyme is one having a catalytic domain based on mesotrypsin (including functional fragments, derivatives, variants, homologs, and/or stabilized mutations thereof). Another preferred adzyme is one having a targeting moiety based on a protein scaffold, such a protein having an immunoglobulin-like fold.

La présente invention a trait à une famille de constructions de protéines, utiles en tant que médicaments et à d'autres fins, désignées <=adzymes>=, comportant un groupe fonctionnel d'adressage etun domaine catalytique. Une <=adzyme>= préférée est celle qui présente un domaine catalytique à base de mésotrypsine (y compris ses fragments, dérivés, variants, homologues, et/ou mutations stabilisées). Une autre <=adzyme>= préférée est celle qui présente un groupe fonctionnel de ciblage à base de squelette protéique, une telle protéine comportant un pli de type immunoglobuline.

Affiliated with

Also associated with

Rating

Adzymes and uses thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Adzymes and uses thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Adzymes and uses thereof will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1581771