Aerosol actuator providing increased respirable fraction

Details Aerosol actuator providing increased respirable fraction Aerosol actuator providing increased respirable fraction

A - Human Necessities

61

M

A61M 15/00 (2006.01) B65D 83/16 (2006.01)

Patent

CA 2090495

2090495 9204070 PCTABS00011 An actuator for use in inhalation therapy comprising a nozzle block (14) having an orifice (24) and at least one bleed hole (18), a deagglomeration chamber, and an exit chamber (32), together configured as a means for increasing the respirable fraction of an aerosol formulation. This invention also provides an actuator as described above in combination with an aerosol canister comprising a pharmaceutical formulation, and a method of administering a pharmaceutical formulation via inhalation therapy. The actuator finds particular use in improving the respirable fraction of drug in aerosol formulations. The actuator also retains non-respirable particles, thus reducing the amount of drug that is inadvertently administered orally.

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