Aerosol formulation for inhalation containing an...

A - Human Necessities – 61 – K

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A61K 9/12 (2006.01) A61K 31/55 (2006.01)

Patent

CA 2628947

The invention relates to specific aqueous aerosol formulations that are devoid of propellant, containing one or more anticholinergic agents of formula (1), in which X~represents an anion. According to the invention, the cation of formula (1') is contained in the preparation at a concentration of between 32 and 54 mg per 100 ml of medicament preparation.

L'invention concerne des formulations d'aérosol aqueuses spécifiques, exemptes de gaz propulseur, contenant un ou plusieurs agents anticholinergiques, représentées par la formule (1) dans laquelle X- est un anion, au moins un acide organique pharmaceutiquement compatible, et éventuellement d'autres agents auxiliaires et/ou complexants pharmaceutiquement compatibles, le cation de la formule (1') étant présent dans la préparation à une concentration de 32 à 54 mg pour 100 ml de préparation pharmaceutique.

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