Aerosol formulation for inhalation containing an...

A - Human Necessities – 61 – K

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A61K 9/00 (2006.01)

Patent

CA 2593272

The invention relates to a pharmaceutical preparation for inhalation, containing a compound of formula (1) as an exclusive active ingredient, wherein X represents an anion which is selected preferably from the groups comprising chloride, bromide, iodide, sulphate, phosphate, methane sulfonate, nitrate, meleate, acetate, citrate, fumarate, tartrate, oxalate, succinate, benzoate and p-toluolsulfonate, as a solvent ethanol or mixtures of ethanol and water, at least one pharmacologically compatible acid thereof, in addition to pharmacologically compatible auxiliary agents and/or complexing agents.

La présente invention concerne des préparations médicamenteuses destinées à l'inhalation et contenant comme unique principe actif un composé de la formule (1) où X' représente un anion qui est, de préférence, sélectionné dans le groupe constitué de chlorure, bromure, iodure, sulfate, phosphate, méthansulfonate, nitrate, maléate, acétate, citrate, fumarate, tartrate, oxalate, succinate, benzoate et p- 0 toluolsulfonate ; comme solvant de l'éthanol ou des mélanges d'éthanol et d'eau, au moins un acide pharmacologiquement compatible et éventuellement d'autres adjuvants pharmacologiquement compatibles et/ou des agents complexants.

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