Aerosol inhaler

A - Human Necessities – 61 – M

Patent

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Details

A61M 15/00 (2006.01) A61K 9/00 (2006.01)

Patent

CA 2396273

A device for delivering metered aerosols comprising an active ingredient in solution in a propellant consisting of a hydrofluoroalkane (HFA), selected from 1,1,1,2-tetrafluoroethane (HFA 134a), 1,1,1,2,3,3,3-heptafluoropropane (HFA 227) or mixtures thereof, a co-solvent such as ethanol and optionally a low-volatility component preferably selected from glycerol, propylene glycol, polyethylene glycol, oleic acid and isopropyl myristate, said device comprising a flat body with a seat for housing the can, an inhalation mouthpiece and an expansion chamber shaped to create a vortex flow of the aerosol particles expelled by the actuator, wherein the actuator orifice diameter is in the range between 0.30 and 0.50 mm.

Dispositif destiné à l'administration d'aérosols dosés qui comprennent: un composant actif en solution dans un agent propulseur constitué d'un hydrofluoroalcane (HFA) sélectionné parmi le 1,1,1,2-tétrafluoroéthane (HFA 134a), le 1,1,1,2,3,3,3-heptafluoropropane (HFA 227) ou des mélanges de ceux-ci, un cosolvant, tel que l'éthanol, et, éventuellement, un composant peu volatil, sélectionné parmi la glycérine, le propylène glycol, le polyéthylène glycol, l'acide oléique et le myristate d'isopropyle. Ledit dispositif comprend un corps plat pourvu d'un siège destiné à recevoir le contenant, un embout d'inhalation et une chambre d'expansion configurée pour créer un écoulement rotationnel de particules d'aérosol expulsées par l'actionneur, le diamètre de l'orifice de cet actionneur étant compris entre 0,3 et 0,5 mm.

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