Aerosols comprising nanoparticle drugs

Details Aerosols comprising nanoparticle drugs Aerosols comprising nanoparticle drugs

A - Human Necessities

61

K

A61K 9/14 (2006.01) A61K 9/16 (2006.01) A61K 9/19 (2006.01) A61K 9/72 (2006.01)

Patent

CA 2350074

The invention discloses aqueous dispersions of nanoparticulate aerosol formulations, dry powder nanoparticulate aerosol formulation, propellant-based aerosol formulations, methods of using the formulations in aerosol delivery devices, and methods of making such formulations. The nanoparticles of the aqueous dispersions or dry powder formulations comprise insoluble drug particles having a surface modifier on the surface thereof.

L'invention porte sur des dispersions aqueuses de formulations aérosol nanoparticulaires, de formulations aérosol nanoparticulaires de poudre sèche, de formulations aérosol à base d'agent propulseur, sur des procédés d'utilisation de ces formulations dans des dispositifs d'administration aérosol et sur des procédés de fabrication de ces formulations. Les nanoparticules des dispersions aqueuses ou des formulations de poudre sèche comprennent des particules de médicaments insolubles possédant sur leur surface un modificateur de surface.

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