Aerothricin analogs, their preparation and use

Details Aerothricin analogs, their preparation and use Aerothricin analogs, their preparation and use

C - Chemistry, Metallurgy

07

K

C07K 7/56 (2006.01) A61K 38/10 (2006.01) A61K 38/12 (2006.01) A61P 31/10 (2006.01) C07K 7/08 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2396174

The present invention relates to novel Aerothricins represented by the Formula (I), wherein R1, R2 and R3 are as defined in Claim 1, and pharmaceutically acceptable salts thereof. The present invention also relates to a pharmaceutical composition comprising an Aerothricin of the Formula (I) and a pharmaceutically acceptable carrier. Furthermore, the present invention relates to the use of such Aerothricins for the preparation of medicaments, as well as to processes for the preparation of the Aerothricins of the Formula (I).

L'invention concerne des aérothricines représentées par la formule (I), dans laquelle R<1>, R<2> et R<3> sont tels que définis dans la revendication 1, ainsi que des sels de ces aérothricines acceptables sur le plan pharmaceutique. Elle concerne aussi une composition pharmaceutique comprenant une aérothricine de formule (I) et un support acceptable sur le plan pharmaceutique. Elle concerne encore l'utilisation de telles aérothricines pour la préparation de médicaments, ainsi que des procédés destinés à la préparation des aérothricines de formule (I).

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