Afamin: a human serum albumin-like protein

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A61K 31/70 (2006.01) A61K 39/395 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C07K 16/46 (2006.01) C07K 19/00 (2006.01) C12N 15/62 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/577 (2006.01)

Patent

CA 2186516

The invention relates to a novel human serum protein referred to as AFM, which has one or more activities in common with human serum albumin, human a-fetoprotein, or human vitamin D binding protein and which has an apparent molecular weight by SDS-PAGE of 87 kd; variants thereof; and related genes, vectors, cells and methods.

La présente invention concerne une nouvelle protéine sérique humaine abrégée en AFM et qui présente une ou plusieurs activités communes à l'albumine sérique humaine, à la foetoprotéine a humaine ou à la protéine humaine de fixation de la vitamine D. Ladite AFM est caractérisée par un poids moléculaire apparent de 87 kd, déterminé par PAGE en présence de SDS. L'invention concerne également certaines de ses variantes, les gènes, les vecteurs, les cellules et les procédés apparentés.

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