Affinity matured crig variants

Details Affinity matured crig variants Affinity matured crig variants

C - Chemistry, Metallurgy

07

K

C07K 14/705 (2006.01) A61P 37/00 (2006.01) G01N 33/68 (2006.01) A61K 38/17 (2006.01)

Patent

CA 2720685

The present invention concerns affinity matured CRIg variants. In particular, the invention concerns CRIg variants having increased binding affinity to C3b and retaining selective binding to C3b over C3.

La présente invention porte sur des variants de CRIg à maturation d'affinité. En particulier, l'invention porte sur des variants de CRIg ayant une affinité de liaison accrue pour C3b et conservant une liaison sélective à C3b sur C3.

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