A - Human Necessities – 61 – L
Patent
A - Human Necessities
61
L
167/327, 195/33
A61L 15/00 (2006.01) A61M 1/36 (2006.01) B01J 20/286 (2006.01) B01J 20/32 (2006.01) G01N 30/02 (2006.01) G01N 30/52 (2006.01) G01N 30/56 (2006.01) G01N 30/88 (2006.01)
Patent
CA 2002310
A method of coating chromatographic particulate supports to provide a biocompatible outer layer of synthetic membrane-type film which prevents the release of fines but permits the adsorption of components to an affinity ligand is described. The matrix is provided with a membrane-type coating, which prevents leaching of fines, with a pore size of at least 20 angstroms. The coating is applied to a solid particulate under conditions where an integral membrane coat will be formed. It may also be necessary to control the size and number of pores of the membranes by treating a suspension of the solid support in a solvent which contains 0.1-1% of the sugport weight of a biocompatible polymer along with 0.5-5% of the weight of said polymer of a dissolved compatible pore-controlling component. The solvent is then removed from the suspension and the membrane-coated material used in extracorporeal treatment of body fluids or in other chromatographic techniques. The coating process can be conducted before or after the particulate support is functionalized and/or derivatized.
Ade & Company
Chembiomed Ltd.
LandOfFree
Affinity supports for hemoperfusion does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Affinity supports for hemoperfusion, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Affinity supports for hemoperfusion will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1730183