Agent for applying to mucosa and method for production thereof

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/726 (2006.01) A61K 9/08 (2006.01) A61K 31/728 (2006.01) A61K 47/48 (2006.01) A61P 17/00 (2006.01)

Patent

CA 2625532

An agent for applying to mucosa capable of persistently exerting a therapeutic effect on disorders such as inflammation and lesions in the mucosa even by a lower frequency of administration because the agent can stay at a diseased site for a long period of time by exhibiting a high staying property in a mucosal epithelial layer is provided, said agent for application to mucosa containing glycosaminoglycan (GAG) into which a hydrophobic group is introduced via a binding chain, as an active ingredient.

La présente invention concerne un agent pour application sur une muqueuse qui est susceptible d'exercer de façon durable un effet thérapeutique sur des troubles tels que des inflammations et des lésions de la muqueuse, même à faible fréquence d'administration, l'agent pouvant se maintenir au niveau d'un site de maladie sur une période de temps prolongée du fait d'une capacité élevée à se maintenir sur la couche épithéliale d'une muqueuse. Ledit agent pour application sur une muqueuse contient un glycosaminoglycane (GAG) dans lequel est introduit un groupement hydrophobe via une chaîne de liaison, au titre de principe actif.

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