C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/09 (2006.01) C12N 5/073 (2010.01) C12N 5/079 (2010.01) A61K 35/48 (2006.01) A61K 38/17 (2006.01) A61K 48/00 (2006.01) A61P 17/00 (2006.01) A61P 25/00 (2006.01) A61P 25/16 (2006.01) A61P 25/28 (2006.01) A61P 43/00 (2006.01) C07K 14/47 (2006.01) C12N 15/85 (2006.01) C12Q 1/02 (2006.01) G01N 33/50 (2006.01) A61K 35/12 (2006.01)
Patent
CA 2467258
A method of obtaining a solution having an activity of inducing the differentiation of embryo stem cells into ectodermal cells or ectoderm-origin cells which involves the step of culturing stroma cells with the use of a liquid medium containing a polyanion compound and then recovering the liquid medium; a solution having an activity of inducing the differentiation of embryo stem cells into ectodermal cells or ectoderm-origin cells which is obtained by using the above method; and an inducer for the differentiation of embryo stem cells into ectodermal cells or ectoderm-origin cells.
Cette invention concerne : un procédé d'obtention d'une solution dont l'activité permet d'induire une différentiation de cellules souches d'embryon entre cellules ectodermiques et cellules d'origine ectodermique. Cette méthode consiste à cultiver des cellules de stroma dans un milieu liquide renfermant un composé polyanionique, puis à récupérer ce milieu ; une solution dont l'activité permet d'induire une différentiation de cellules souches d'embryon entre cellules ectodermiques et cellules d'origine ectodermique et qui s'obtient par la méthodes susmentionnée ; et un inducteur de différentiation de cellules souches d'embryon entre cellules ectodermiques et cellules d'origine ectodermique.
Iwata Hiroo
Kobori Masato
Murakami Yoshinobu
Sasai Yoshiki
Satoh Mitsuo
Goudreau Gage Dubuc
Iwata Hiroo
Kyowa Hakko Kirin Co. Ltd.
Kyowa Hakko Kogyo Co. Ltd.
Sasai Yoshiki
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