Agent for promoting proliferation of hematopoietic stem cells

Details Agent for promoting proliferation of hematopoietic stem cells Agent for promoting proliferation of hematopoietic stem cells

C - Chemistry, Metallurgy

07

K

C07K 14/52 (2006.01) A61K 38/19 (2006.01) C12N 5/06 (2006.01) C12N 5/08 (2006.01) C12Q 1/02 (2006.01)

Patent

CA 2228084

An agent for promoting the proliferation of hematopoietic stem cells is provided, which comprises OSM as an effective ingredient. OSM has the activity to promote the proliferation of hematopoietic stem cells, paving the new way for the treatment of the cellular disorder of hemocytes. The in vitro culture of the AGM region is also provided, which enables the screening of compounds for the activity to promote the proliferation of hematopoietic stem cells.

Divulgation d'un agent favorisant la prolifération des cellules souches hématopoïétiques qui contient de l'oncostatine M comme ingrédient efficace. L'oncostatine M favorise la prolifération des cellules souches hématopoïétiques, pavant ainsi une nouvelle voie pour le traitement des troubles des cellules sanguines. La culture in vitro de la région de l'aorte, des gonades et du mésonéphros (AGM), également dévoilée, permet de cribler les composés favorisant la prolifération des cellules souches hématopoïétiques.

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