Agent for prophylaxis and treatment of glaucoma

Details Agent for prophylaxis and treatment of glaucoma Agent for prophylaxis and treatment of glaucoma

A - Human Necessities

61

K

A61K 31/4409 (2006.01) A61K 9/08 (2006.01) A61K 31/437 (2006.01) A61P 27/06 (2006.01)

Patent

CA 2307285

An agent for the prophylaxis and treatment of glaucoma, which contains a compound having a Rho kinase inhibitory activity, particularly an agent for the prophylaxis and treatment of glaucoma, which contains a compound of the formula (I) (see formula I) wherein each symbol is as defined in the specification, as the compound having a Rho kinase inhibitory activity, is provided. The agent for the prophylaxis and treatment of glaucoma of the present invention is a novel agent for the prophylaxis and treatment of glaucoma and has intraocular pressure lowering action, optic disc blood flow improving action and aqueous humor outflow promoting action.

L'invention concerne des médicaments préventifs/curatifs pour le glaucome, qui contiennent des composés présentant une activité inhibitrice de la Rho kinase, en particulier ceux représentés par la formule générale (I), formule dans laquelle chaque symbole correspond à la définition donnée dans la description. Ces médicaments préventifs/curatifs sont de nouveaux médicaments qui ont pour effets d'abaisser la pression intraoculaire, d'améliorer le flux sanguin dans la papille optique et de favoriser l'écoulement de l'humeur aqueuse.

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