Agent for prophylaxis and treatment of interstitial...

Details Agent for prophylaxis and treatment of interstitial... Agent for prophylaxis and treatment of interstitial...

A - Human Necessities

61

K

A61K 31/4409 (2006.01) A61K 31/437 (2006.01) A61P 11/00 (2006.01)

Patent

CA 2368675

An agent for the prophylaxis and treatment of interstitial pneumonia and pulmonary fibrosis, which contains a compound having a Rho kinase inhibitory activity, particularly an agent for the prophylaxis and treatment of interstitial pneumonia and pulmonary fibrosis, which contains a compound of the formula (I) (see formula I) wherein each symbol is as defined in the specification, as the compound having a Rho kinase inhibitory activity, is provided.

La présente invention concerne des prophylaxies/remèdes pour la pneumonie interstitielle et la fibrose pulmonaire contenant des composés présentant une activité inhibitrice du Rho kinase. En particulier des prophylaxies/remèdes pour la pneumonie interstitielle et la fibrose pulmonaire contenant, en tant que composés à activité inhibitrice du Rho kinase, des composés correspondant à la formule générale (I), par exemple, (+)-trans-4-(1-aminoéthyle)-1-(4-pyridylcarbamoyle)cyclohexane, dans laquelle chaque symbole est tel que défini dans la description.

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