Agent for protecting central nerve cells and enhancing...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/195 (2006.01) A61K 31/198 (2006.01) A61K 31/23 (2006.01) C12N 5/16 (2006.01)

Patent

CA 2298795

A cell survival promoting agent for central nervous cells, containing as the active ingredient a compound selected from the group consisting of L-serine, glycine, and fatty acid derivatives thereof; and an agent for prevention and/or treatment of a lowering in the function of brains, containing the compound as the active ingredient. The cell survival promoting agent functions to protect brain cells to inhibit cell death and, at the same time, to prolong the life of the cells. It can inhibit the death of brain cells induced, for example, by cerebral hemorrhage, cerebral infarction, and cerebral edema and the rise of the intracranial temperature caused by cephalic lesion or the like.

Agent servant à promouvoir la survie des cellules du système nerveux central et contenant en tant qu'ingrédient actif, un composé sélectionné dans le groupe constitué par L-sérine, glycine et des dérivés d'acides gras de ces derniers; agent prophylactique ou thérapeutique servant à traiter la diminution de la fonction cérébrale et contenant ce composé en tant qu'ingrédient actif. Cet agent promoteur de la survie cellulaire sert à protéger les cellules du cerveau afin d'inhiber la mort cellulaire et de prolonger simultanément la vie des cellules. Il peut inhiber la mort de cellules du cerveau provoquée, par exemple, par une hémorragie cérébrale, un infarctus cérébral, un oedème cérébral ou par la montée de la température intracrânienne provoquée par une lésion, telle qu'une lésion céphalique.

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