Agent for reducing detergent irritation to skin and eyes

C - Chemistry – Metallurgy – 11 – D

Patent

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Details

530/15.12, 134/3

C11D 1/65 (2006.01) A61K 8/64 (2006.01) A61K 8/65 (2006.01) C11D 3/33 (2006.01) C11D 3/384 (2006.01)

Patent

CA 1224211

ABSTRACT OF THE DISCLOSURE A water-soluble, positively charged, partially hydrolyzed, protein fraction containing a high concentration of basic amino acids, having an isoionic point greater than 7, a Bloom gel value of zero and a molecular weight of about 600 to 12,000 is disclosed together with liquid detergent compositions having reduced skin and eye irritation properties which contain 10% to 50%, by weight, of a water-soluble, skin-irritating anionic detergent and 0.2% to 5%, by weight, of said protein fraction in an aqueous vehicle. Further, the method of preparing said protein fraction comprising the steps of (a) adjusting the pH of a hydrolyzed collagen protein mixture containing a high concentration of basic amino acids and having a molecular weight of about 600 to 12,000 to the range of 7 to 12; (b) treating the mixture of step (a) with an anionic ion exchange resin to absorb negatively charged groups from the protein onto the resin and to substitute the negatively charged groups from said resin therefor ; (c) dialyzing the mixture from step (b) to remove said negatively charged groups; and (d) recovering said protein fraction having a pI point greater than 7 is disclosed.

423508

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