Agent for relieving side effects caused by immunosuppressants

A - Human Necessities – 61 – K

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Details

A61K 38/18 (2006.01) A61K 45/06 (2006.01)

Patent

CA 2185794

The present invention relates to an agent for relieving side effects caused by immunosuppressants, which comprises HGF (Hepatocyte growth factor) as an active component, a method for relieving side effects caused by immunosuppressants, which comprises administration of HGF and use of HGF for producing an agent for relieving the side effects. HGF as an active component can reduce multiple-organ or systemic side effects caused by immunosuppressants. Therefore, according to the present invention, restrictions of use and dose of immunosuppressants are reduced, success rate of organ transplantation and cure rate of various patients to which the immunosuppressants are administered can be improved and at the same time burden of the patients can be remarkably reduced.

L'invention concerne un médicament contenant un facteur de croissance des hépatocytes (HGF), utilisé comme ingrédient actif pour soulager les effets secondaires provoqués par des immunodépresseurs, un procédé de soulagement d'effets secondaires provoqués par des immunodépresseurs par administration de HGF, ainsi que l'utilisation de ce dernier dans la production du médicament. Etant donné que le HGF est utilisé pour soulager des effets secondaires sur plusieurs organes ou sur l'organisme, ce médicament peut influer sur les limitations apportées aux schémas posologiques d'immunodépresseurs, il peut améliorer à la fois la vitesse de cicatrisation dans diverses maladies et le pourcentage de succès de transplantations d'organes dans lesquelles on utilise des immunodépresseurs, et il est remarquable dans son effet de soulagement des patients.

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