Agent for the detection of leukocytes

C - Chemistry – Metallurgy – 09 – B

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167/44, 530/5, 2

C09B 57/00 (2006.01) C07D 327/04 (2006.01) G01N 33/50 (2006.01)

Patent

CA 1129848

ABSTRACT OF THE DISCLOSURE Sulphonphthaleins are employed as chromogens in diag- nostic agents for the detection of leukocytes in body fluids; the chromogens permit an accurate detection at low leukocyte concentration in fluids such as urine: the sulphonphthaleins have the formula - Image in which R1 is a carboxylic acid residue, unsubstituted or substituted by halogen or a lower alkoxy radical, or is an amino acid or peptide residue provided with a nitrogen pro- tective group, R2 is a halogen atom or a lower alkyl radical and R3 and R4, which are the same or different, are hydrogen or halogen atoms.

329713

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