Agent for the prophylaxis of atopy and methods for preparing...

A - Human Necessities – 61 – K

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167/122, 167/127

A61K 33/26 (2006.01) A23L 1/30 (2006.01) A61K 31/557 (2006.01) A61K 33/30 (2006.01) A61K 38/32 (2006.01)

Patent

CA 2013809

The subject invention provides an agent and a method for atopy prophylaxis. Supplying gamma-linolenic acid, dihomo-gamma- linolenic acid, the physiologically compatible salts, esters, amides, phospholipids, glycolipids thereof, and Prostaglandin E1 (PGE1), PGE1 derivatives, PGE1 analogs to babies can prevent a subsequent occurrence of manifest atopy forms. The agents according to the invention are preferably contained in a baby food and/or should be supplied to the baby together therewith. In a further preferred embodiment the agent contains a thymus hormone, or thymus hormones provided in combination with the agent. Further provided for is the use of Prostaglandin E1, its derivatives and analogs and the physiologically compatible esters, amides, phospholipids and glycolipids thereof in a pharmacologically effective dosage form for the topical or inhalative treatment of acute manifest atopy in the dermal and mucosal areas. The substance used according to the invention are preferably used in combination with gamma-linolenic acid, 15-hydroxydihomo-gamma-linolenic acid and dihomo-gamma-linolenic acid, the physiologically compatible salts, esters, amides, phospholipids and glycolipids thereof.

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