Agent for the treatment of bladder irritative symptoms...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/381 (2006.01) A61K 31/38 (2006.01) A61K 31/44 (2006.01) A61P 13/10 (2006.01) C12Q 1/00 (2006.01) C12Q 1/02 (2006.01)

Patent

CA 2442452

The present invention provides an agent for the treatment of bladder irritative symptoms accompanied by benign prostatic hyperplasia, comprising, as an active ingredient, a compound having a slowly-inactivating A-type K+ channel opening activity or a pharmaceutically acceptable salt thereof, and a method for screening agents for the treatment of bladder irritative symptoms accompanied by benign prostatic hyperplasia, comprising measuring a slowly- inactivating A-type K+ channel opening activity as an index.

L'invention concerne un agent destiné au traitement de symptômes d'irritation de la vessie accompagnés d'hyperplasie bénigne de la prostate, qui comprend, comme ingrédient actif, un composé ayant une activité d'ouverture de canaux à K?+¿ type A lentement inactivants ou un sel de ce dernier pharmaceutiquement acceptable, ainsi qu'un procédé de criblage d'agents destinés au traitement de symptômes d'irritation de la vessie accompagnés d'hyperplasie bénigne de la prostate, qui consiste à mesurer, comme indice, une activité d'ouverture de canaux à K?+¿ type A lentement inactivants.

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