A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/381 (2006.01) A61K 31/38 (2006.01) A61P 13/10 (2006.01) C07D 495/04 (2006.01) C12Q 1/00 (2006.01) C12Q 1/02 (2006.01)
Patent
CA 2442437
The present invention provides an agent for the treatment of overactive bladder, comprising, as an active ingredient, a compound having a slowly- inactivating A-type K+ channel opening activity or a pharmaceutically acceptable salt thereof, and a method for screening agents for the treatment of overactive bladder, comprising measuring a slowly-inactivating A-type K+ channel opening activity as an index.
L'invention concerne un agent destiné au traitement de la vessie hyperactive. Cet agent comprend, comme principe actif, un composé présentant une activité d'ouverture de canal K?+¿ de type A à inactivation lente ou un sel acceptable sur le plan pharmaceutique de celui-ci, ainsi qu'un procédé de balayage d'agents destinés au traitement de la vessie hyperactive consistant à mesurer une activité d'ouverture de canal K?+¿ de type A à inactivation lente comme un indice.
Atsuki Kaoru
Degroat William C.
Karasawa Akira
Ohno Tetsuji
Sculporeanu Adrian
Goudreau Gage Dubuc
Kyowa Hakko Kogyo Co. Ltd.
University Of Pittsburgh
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