Agent for therapeutic and prophylactic treatment of...

A - Human Necessities – 61 – K

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A61K 31/4015 (2006.01) A61P 25/04 (2006.01) C07D 207/263 (2006.01) C07D 207/27 (2006.01) C07D 207/273 (2006.01)

Patent

CA 2433039

Medicines for treatment and/or prevention of neurogenic pain, containing as the active ingredient compounds represented by the general formula (|) or pharmaceutically acceptable salts thereof:(|) wherein R1 is hydrogen or hydroxyl; R2 is hydrogen or C1-3 alkyl; R3 is phenyl which may have one to three substituents selected from the group consisting of halogeno, hydroxyl, C1-3 alkyl, and C1-3 alkoxy, or -NH-R4 (wherein R4 is phenyl which may have one to three substituents selected from the group consisting of halogeno, hydroxyl, C1-3 alkyl, and C1-3 alkoxy, or hydrogen); and n is 0 or 1.

L'invention concerne des médicaments permettant de traiter ou de prévenir une douleur neurologique, qui contiennent comme principe actif des composés représentés par la formule (I) ou des sels de ceux-ci pharmaceutiquement acceptables. Dans cette formule, R1 représente hydrogène ou hydroxyle; R2 représente hydrogène ou C1-3 alkyle; R3 représente phényle pouvant comprendre un à trois substituants sélectionnés dans le groupe constitué par halogéno, hydroxyle, C1-3 alkyle et C1-3 alcoxy, ou -NR-R4 (où R4 représente phényle pouvant comprendre un à trois substituants sélectionnés dans le groupe constitué par halogéno, hydroxyle, C1-3 alkyle et C1-3 alcoxy ou hydrogène; n est un entier égal à 0 ou 1.

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