Agent for treatment of pemphigoid

A - Human Necessities – 61 – K

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A61K 38/21 (2006.01) A61K 45/00 (2006.01) A61P 17/00 (2006.01) A61P 37/02 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2511209

It is intended to provide a remedy for pemphigoid. To use as a remedy for pemphigoid, IFN-.gamma. is administered by intravenous drip in a daily dose of 2,000,000 JRU for 7 days. Depending on the conditions, side effects and age, the administration dose may be altered or the intravenous drip may be carried out once several days. It appears that IFN-.gamma. is efficacious against pemphigoid because of showing a quick action thereon with little side effect. Concerning the function mechanism, it is assumed that IFN-.gamma. inhibits the migration and function of eosinophils seemingly participating directly in the onset of pemphigoid.

L'invention concerne un médicament permettant de traiter la pemphigoïde. L'IFN-.UPSILON. est administré, en tant que remède contre la pemphigoïde, par goutte-à-goutte intraveineux en dose journalière de 2 000 000 JRU pendant 7 jours. En fonction des affections, des effets secondaires et de l'âge, la dose administrée peut être modifiée, ou le goutte-à-goutte intraveineux peut être posé une fois tous les deux ou trois jours. L'IFN-.UPSILON. est efficace contre la pemphigoïde car elle a une action rapide sur celle-ci avec peu d'effets secondaires. Concernant le mécanisme fonctionnel, l'IFN-.UPSILON. inhibe la migration et la fonction des éosinophiles qui semblent être directement impliqués dans le déclenchement de la pemphigoïde.

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